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CCL21 Mouse anti-Human, Clone: 54111, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA523751

Catalog No. PIMA523751


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Description

Description

In Western blots, shows 100% cross-reactivity with recombit human (rh) CCL24. Under reducing conditions, this antibody shows approximately 10-50% cross-reactivity with rhCCL2, 8, 13, 28, and rmCCL2. This antibody does not cross-react with rhCCL1, 3, 4, 5, 7, 9, 11, 14a, 15, 17, 18, 19, 20, 22, 23, 25, rmCCL1, 3, 4, 6, 7, 9, 11, 12, 19, 20, 21, 22, 24, 25, 28, or rrCCL20. Reconstitute at 0.5 mg/mL in sterile PBS.

This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19).
Specifications

Specifications

CCL21
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
O00585
6Ckine, CKb9, ECL, SCYA21, SLC, TCA4, C-C motif chemokine 21, Efficient Chemoattractant for Lymphocytes, beta chemokine exodus-2, beta-chemokine exodus-2, exodus-2, secondary lymphoid tissue chemokine, secondary lymphoid-tissue chemokine, small inducible cytokine subfamily A (Cys-Cys), member 21, sma
Mouse
IgG1
500 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
6366
ELISA, Western Blot
54111
Unconjugated
CCL21
Lyophilized
CCL21
E. coli-derived recombit human CCL21/6Ckine Ser24-Pro134
Protein A/G
RUO
Antibody
Monoclonal
Human
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