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CCL21 Rat anti-Mouse, Clone: 59106, Invitrogen™

Rat Monoclonal Antibody

Manufacturer:  Invitrogen MA523755

Catalog No. PIMA523755


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Description

Description

This antibody does not cross-react with recombit human (rh) 6Ckine, rhMIP-1 alpha, rhMIP-1 beta, recombit mouse (rm) MIP-1 alpha, rmMIP-1 beta, rhMIP-1 gamma, rmMIP-1 gamma, rmMIP-2, rhMIP-3 alpha, rmMIP-3 alpha, rhMIP-3 beta, rmMIP-3 beta, rhTeck, or rmTeck. Reconstitute at 0.5 mg/mL in sterile PBS.

This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19).
Specifications

Specifications

CCL21
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
P84444
6Ckine, CKb9, ECL, SCYA21, SLC, TCA4, C-C motif chemokine 21, Efficient Chemoattractant for Lymphocytes, beta chemokine exodus-2, beta-chemokine exodus-2, exodus-2, secondary lymphoid tissue chemokine, secondary lymphoid-tissue chemokine, small inducible cytokine subfamily A (Cys-Cys), member 21, sma
Rat
IgG2b
500 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
18829
ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Western Blot
59106
Unconjugated
Ccl21a
Lyophilized
CCL21A
E. coli-derived recombit mouse CCL21/6Ckine Ser24-Gly133
Protein A/G
RUO
Antibody
Monoclonal
Mouse
Documents
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