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CCR1 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA141062

Catalog No. 01-676-659


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Description

Description

Chemokines play important roles in inflammation and critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. One of the CCR receptors, CCR1, is expressed on neutrophils, monocytes, lymphocytes, and eosinophils and binds the leukocyte chemoattractant and hemopoiesis regulator macrophage-inflammatory protein (MIP-1 ), eotaxin, as well as several other related chemokines. Mice lacking the chemokine receptor CCR1 have defects in neutrophil trafficking and proliferation.

Suggested positive control: A375, antigen standard for CCR1 (transient overexpression lysate).
Specifications

Specifications

CCR1
Polyclonal
Unconjugated
CCR1
Liquid
CCR1
Synthetic peptide corresponding to human CCR1.
Protein G
RUO
Antibody
Polyclonal
Human, Mouse
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 0.02% sodium azide
P32246, P51675
CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
1230, 12768
Documents
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