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CCR1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA524785

Catalog No. PIPA524785


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Description

Description

CCR1 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p.
Specifications

Specifications

CCR1
Polyclonal
Unconjugated
CCR1
Liquid
CCR1
KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CCR1
Antigen Affinity Chromatography, Protein A
RUO
Antibody
Polyclonal
Human
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
0.5 mg/mL
PBS with 0.09% sodium azide
P32246
CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
1230
Documents
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