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CCR3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA141377

Catalog No. 01-675-508


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Description

Description

Suggested positive control: antigen standard for CCR3 (transient overexpression lysate), Daudi.

CCR3 (C-C chemokine receptor type 3) binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1 delta. CCR3 trasnduces a signal by increasing the intracellular calcium ions level. It also serves as an alternative co-receptor with CD4 for HIV-1 infection. Other chemokines play important roles in inflammation and are critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines.
Specifications

Specifications

CCR3
Polyclonal
Unconjugated
CCR3
Liquid
CCR3
Synthetic peptide corresponding to a portion of human CCR3 protein.
Protein G
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Western Blot
0.5 mg/mL
PBS with no preservative
P51677, P51678, O54814
CC-CKR-3, CKR3, CMKBR3, MGC102841
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
117027, 1232, 12771
Documents
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