CCR4 Mouse anti-Human, Clone: KH-4F5-D3, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA117770
Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines.This antibody recognizes native human CCR4 protein expressed in transfected mammalian cells.
|PBS with no preservative; pH 7.2|
|CC-CKR-4, CKR4, CMKBR4, ChemR13, HGCN:14099, K5-5, MGC88293|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence|
|Synthetic peptide corresponding to human CCR4.|
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