CCR6 Goat anti-Human, Mouse, Polyclonal, Invitrogen
Goat Polyclonal Antibody
Manufacturer: Invitrogen PA121615
PA1-21615 detects CCR6 in human samples. This antibody does not detect mouse CCR6. PA1-21615 has been successfully used in ELISA, western blot, and immunohistochemistry (paraffin) procedures. The PA1-21615 immunogen is a synthetic peptide corresponding to residues Y(18) F V S V N T S Y Y S V D S E M L L C S L Q E V R Q F S R(46) of human CCR6. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.Receptors for the C-C chemokine family include CCR-1, CCR-2A, CCR-3, CCR-4, CCR-5 and the Duffy blood group antigen. The C-C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation. CCR6 in particular is a G-protein-coupled receptor that binds MIP-3a. It is expressed on T cells, B cells and subsets of dendritic cells. It has been implicated in the adaptive immune response.
|Synthetic peptide corresponding to residues Y(18) F V S V N T S Y Y S V D S E M L L C S L Q E V R Q F S R(46) of human CCR6.|
|Antigen affinity chromatography|
|ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot|
|0.01M potassium phosphate with 0.14M NaCl, 1mg/mL BSA and 0.1% sodium azide; pH 7.2|
|BN-1, CKR-L3, CKR6, CKRL3, CMKBR6, DCR2, DRY-6, GPR-CY4, GPR29, GPRCY4, STRL22|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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