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CCR8 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523987

Catalog No. PIPA523987


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Description

Description

CCR8 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. CCR8 is located at the chemokine receptor gene cluster region.
Specifications

Specifications

CCR8
Polyclonal
Unconjugated
CCR8
Liquid
CCR8
KLH conjugated synthetic peptide between 290-317 amino acids from the C-terminal region of human CCR8
Protein A, Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
Flow Cytometry, Western Blot
0.5 mg/mL
PBS with 0.09% sodium azide
P51685
CDw198, CKR-L1, CKRL1, CMKBR8, CMKBRL2, CY6, GPR-CY6, MGC129966, MGC129973, TER1
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
1237
Documents
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