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CD103 Rat anti-Mouse, Brilliant Violet 786, Clone: M290, BD

Rat Monoclonal Antibody

Manufacturer:  BD Biosciences 564322

Catalog No. BDB564322

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The M290 antibody specificaly binds to CD103, the α chain of α IEL β 7 integrin. CD103 has a unique and fairly restricted tissue distribution. It is expressed on almost all intestinal intraepithelial lymphocytes (IEL), on dendritic epidermal T cells (DEC), on subpopulations of peripheral T cells, and on distinct subsets of fetal, neonatal, and adult thymocytes. E-cadherin is the epithelial-cell ligand for α IEL β 7 integrin. The ordered expression of α IEL during thymocyte development (which occurs under the influence of the thymic epithelium), the high level of expression of α α IEL β 7-mediated adhesion in in vitro assays.



Brilliant Violet 786
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
IgG2a, κ
Flow Cytometry
Itgae; Integrin alpha-E; αE; alpha-E1; ITAE; Integrin αIEL chain; aM290
Affinity Purified
Mouse Intestinal Epithelial Cells
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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