CD103 Rat anti-Mouse, PerCP-Cy5.5, Clone: M290, BD
Rat Monoclonal Antibody
Manufacturer: BD Biosciences 563637
The M290 antibody specificaly binds to CD103, the α chain of αIELβ7 integrin. CD103 has a unique and fairly restricted tissue distribution. It is expressed on almost all intestinal intraepithelial lymphocytes (IEL), on dendritic epidermal T cells (DEC), on subpopulations of peripheral T cells, and on distinct subsets of fetal, neonatal, and adult thymocytes. E-cadherin is the epithelial-cell ligand for αIELβ7 integrin. The ordered expression of αIEL during thymocyte development (which occurs under the influence of the thymic epithelium), the high level of expression of ααIELβ7-mediated adhesion in in vitro assays.
|Aqueous buffered solution containing ≤0.09% sodium azide.|
|Itgae; Integrin alpha-E; αE; alpha-E1; ITAE; Integrin αIEL chain; aM290|
|Mouse Intestinal Epithelial Cells|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
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