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CD105 Rat anti-Mouse, Clone: 209701, Invitrogen™

Rat Monoclonal Antibody

Manufacturer:  Invitrogen MA523894

Catalog No. PIMA523894


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Description

Description

In Western blots, this antibody shows 100% cross-reactivity with recombit human Endoglin. Reconstitute at 0.5 mg/mL in sterile PBS.

CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.
Specifications

Specifications

CD105
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
Q63961
CD105, END, HHT1, ORW, ORW1, CD105 antigen, ENG
Rat
IgG2A
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
13805
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), Western Blot
209701
Unconjugated
Eng
Lyophilized
ENG
Mouse myeloma cell line NS0-derived recombit mouse Endoglin Glu21-Gly581 (predicted)
Protein A/G
RUO
Antibody
Monoclonal
Mouse
Documents
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