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CD105, Polyclonal, Invitrogen™
Description
Endoglin, also called CD105, is a homodimeric membrane glycoprotein primarily associated with human vascular endothelium. It is also found on bone marrow proerythroblasts, activated monocytes, and lymphoblasts in childhood leukemia. Endoglin is a component of the transforming growth factor beta receptor complex, as it binds TGFB1 with high affinity.
Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 30 min at room temperature. A suggested positive control is tonsil tissue.
Specifications
Specifications
| Antigen | CD105 |
| Applications | Immunohistochemistry (Paraffin), Immunoprecipitation |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Dilution | Assay Dependent |
| Gene | ENG |
| Gene Accession No. | P17813 |
| Gene Alias | CD105, END, HHT1, ORW, ORW1, CD105 antigen, ENG |
| Gene Symbols | ENG |
| Host Species | Rabbit |
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