CD105, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA137372

Catalog No. 01-673-246

Description

Endoglin, also called CD105, is a homodimeric membrane glycoprotein primarily associated with human vascular endothelium. It is also found on bone marrow proerythroblasts, activated monocytes, and lymphoblasts in childhood leukemia. Endoglin is a component of the transforming growth factor beta receptor complex, as it binds TGFB1 with high affinity.

Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 30 min at room temperature. A suggested positive control is tonsil tissue.

Specifications

• Antigen: CD105
• Classification: Polyclonal
• Dilution: Assay Dependent
• Gene Accession No.: P17813
• Gene Symbols: ENG
• Immunogen: Recombinant protein encoding 26-176 aa of human CD105
• Quantity: 1 mL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation
• Conjugate: Unconjugated
• Gene: ENG
• Gene Alias: CD105, END, HHT1, ORW, ORW1, CD105 antigen, ENG
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2022
• Content And Storage: Store at 4°C, do not freeze
• Form: Liquid