CD107b Rat anti-Mouse, Brilliant Violet 421, Clone: ABL-93, BD

Rat Monoclonal Antibody

Supplier:  BD Biosciences 564249

Catalog No. BDB564249

Description

The ABL-93 monoclonal antibody specifically recognizes CD107b which is also known as Lysosome-associated membrane protein 2 (LAMP2/LAMP-2), Lysosomal membrane glycoprotein type B (LGP-B), and Mac-3. CD107b is a type I lysosomal transmembrane glycoprotein that serves as a useful marker to distinguish lysosomes from other cellular organelles. Mouse CD107b consists of a ∽40-kDa core protein which is heavily glycosylated to form heterogeneous mature glycoproteins of 110-120 kDa. It is principally expressed in epithelial cells and macrophages in a variety of organs in normal and Beige mutant mice.

The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50-nm filter). BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates.

Specifications

• Antigen: CD107b
• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Description: Lamp2; LAMP-2; LAMP II; Lysosomal-associated membrane protein 2; LGP-B
• Host Species: Rat
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Mouse
• Isotype: IgG2a λ

• Applications: Flow Cytometry, Immunocytochemistry
• Clone: ABL-93
• Conjugate: Brilliant Violet 421
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Immunogen: Glycoproteins purified from BALB/c mouse embryo 3T3 cell line
• Quantity: 50 μg
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.