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CD11A Mouse anti-Human, Brilliant Violet 510, Clone: HI111, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 563480

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Catalog No. BDB563480


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Description

Description

The HI111 monoclonal antibody specifically binds to CD11a, the 180 kDa integrin α chain. This type I transmembrane glycoprotein associates with CD18 (integrin β2) to form the heterodimeric glycoprotein CD11a/CD18. This heterodimer is also known as the lymphocyte (leukocytes) function associated antigen-1 (LFA-1) that is expressed on all leukocytes. LFA-1 is an adhesion molecule involved in lymphocyte and granulocyte functions. LFA-1 mediates adhesion of lymphoid cells to the vascular endothelium in association with its ligand, and the intracellular adhesion molecule-1 (ICAM-1), CD54. Other ligands are ICAM-2 (CD102) and ICAM-3 (CD50).

Specifications

Specifications

CD11a
HI111
LFA-1α; Lymphocyte (Leukocyte) function-associated antigen 1 α chain; ITGAL
Affinity Purified
IgG1, κ
RUO
Primary
Baboon, Cynomolgus, Human, Rhesus
Flow Cytometry
Brilliant Violet 510
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Murine
25 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Documents
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