CD11c Hamster anti-Mouse, Brilliant Violet 786, Clone: HL3, BD
Hamster Monoclonal Antibody
Manufacturer: BD Biosciences 563735
The HL3 monoclonal antibody specifically binds to the integrin α x chain of gp150, 95 (CD11c/CD18). CD11c is expressed on dendritic cells, CD4- CD8+ intestinal intraepithelial lymphocytes (IEL) and some NK cells. It is upregulated on IEL and lymph-node T cells following in vivo activation. Cells of the monocyte/macrophage lineage have been reported to express low levels of CD11c. CD11c plays a role in binding of iC3b.
The antibody was conjugated to BD Horizon BV786 which is part of the BD Horizon Brilliant Violet family of dyes. This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 786-nm. BD Horizon BV786 can be excited by the violet laser and detected in a filter used to detect Cy7-like dyes (eg, 780/60-nm filter).
|Brilliant Violet 786|
|Aqueous buffered solution containing BSA and ≤0.09% sodium azide.|
|Cd11c; Itgax; Integrin alpha-X; Integrin αX; Cr4; Complement receptor 4|
|C57BL/6 Mouse Intestinal Intraepithelial Lymphocytes|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
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