CD124 Rat anti-Mouse, Brilliant Violet 421, Clone: mIL4R-M1, BD
Rat Monoclonal Antibody
Manufacturer: BD Biosciences 564086
The mIL4R-M1 monoclonal antibody specifically binds to CD124 which is also known as the α subunit of the mouse Interleukin-4 Receptor (IL-4R α ). The mouse IL-4R α is a 140 kDa transmembrane glycoprotein that is expressed by B and T lymphocytes and a variety of other hematopoietic and nonhematopoietic cells and cell lines. The cell surface IL-4R α chain binds IL-4 with high affinity and associates with either the common γchain (IL-4R α / γα (sIL-4R) that result either from enzymatic cleavage of the cell surface extracellular IL-4R α domain or from differential mRNAsplicing and secretion by cells. These sIL-4R retain their high-affinity ligand binding domain and appear to either enhance or inhibit IL-4-mediated functions depending on the relative local levels of IL-4 and sIL-4R.
|Brilliant Violet 421|
|Aqueous buffered solution containing BSA and ≤0.09% sodium azide.|
|Il4r; IL-4Rα; Il4ra; IL-4RA; IL-4R-alpha; IL4-BP; IL-4 Receptor α chain|
|Mouse CTLL-19.4 T Cell Line|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
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