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CD13 Mouse anti-Human, Non-human primate, Clone: WM15, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA119359

Catalog No. 01-676-115


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Description

Description

CD13 (ANPEP) is a 150-170 kDa type II transmembrane zinc-binding ectopeptidase expressed on various cell types. CD13 is a metalloprotease that preferentially catalyzes removal of neutral amino acids from small peptides, thus activating or inactivating bioactive peptides. CD13 also has a role in extracellular matrix degradation, antigen processing and signal transduction, is important in inflammatory responses, regulates intercellular contact, cell motility and vascularization. CD13 is expressed by granulocytes, monocytes, myeloid leukemia cells, and is involved in protection of leukemic cells against apoptosis and its expression associated with poor prognosis of carcinomas. CD13 functions as an aminopeptidase enzyme and is also alpha receptor for coronavirus.
Specifications

Specifications

CD13
Monoclonal
1 mg/mL
PBS with 15mM sodium azide; pH 7.4
P15144
AP-M, AP-N, Apn, Cd13, P150, alanyl aminopeptidase, aminopeptidase M, aminopeptidase N, aminopeptidase N/CD13, membrane protein p161, microsomal aminopeptidase
Mouse
IgG1
100 μg
4° C, do not freeze
Primary
290
Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunoprecipitation
WM15
Unconjugated
ANPEP
Liquid
ANPEP
Human AML cells.
Purified
RUO
Antibody
Monoclonal
Human, Non-human Primate
Documents
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