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OX40 Rat anti-Human, FITC, Clone: 443318, Invitrogen™

Rat Monoclonal Antibody

Manufacturer:  Invitrogen MA523610

Catalog No. PIMA523610


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Description

Description

In Western blots, no cross-reactivity with recombit human (rh) 4-1BB, rhBAFF R, rhCD27, rhCD30, rhCD40, rhDR3, rhDR6, rhEDAR, rhFAS, rhGITR, rhHVEM, rhLT beta R, rhNGF R, rhRANK, rhRELT, rhTAJ, rhTNF RI, rhTNF RII, rhTRAIL, rhTRAIL R4, rhTRAIL R3, rhTWEAK R, or rhXEDAR is observed.

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.
Specifications

Specifications

OX40
Monoclonal
FITC
TNFRSF4
Liquid
TNFRSF4
Mouse myeloma cell line NS0-derived recombit human OX40/TNFRSF4 Leu29-Ala216
Protein A/G
RUO
Antibody
Monoclonal
Human
Flow Cytometry
443318
Buffered saline solution with BSA and 0.09% sodium azide
P43489
cluster designation 134, TNFRSF4
Rat
IgG2A
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
7293
Documents
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