OX40 Rat anti-Human, FITC, Clone: 443318, Invitrogen
Rat Monoclonal Antibody
Manufacturer: Invitrogen MA523610
In Western blots, no cross-reactivity with recombit human (rh) 4-1BB, rhBAFF R, rhCD27, rhCD30, rhCD40, rhDR3, rhDR6, rhEDAR, rhFAS, rhGITR, rhHVEM, rhLT beta R, rhNGF R, rhRANK, rhRELT, rhTAJ, rhTNF RI, rhTNF RII, rhTRAIL, rhTRAIL R4, rhTRAIL R3, rhTWEAK R, or rhXEDAR is observed.The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.
|Mouse myeloma cell line NS0-derived recombit human OX40/TNFRSF4 Leu29-Ala216|
|Buffered saline solution with BSA and 0.09% sodium azide|
|cluster designation 134, TNFRSF4|
|4° C, store in dark, DO NOT FREEZE!|
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