Thermo Scientific Lab Vision CD137 (4-1BB) Ab-1, Mouse Monoclonal Antibody
Ensure accurate, reproducible results in immunofluorescence and flow cytometry applications with Thermo Scientific CD137 (4-1BB) Ab-1, Mouse Monoclonal Antibody.
Manufacturer: Thermo Scientific MS621P
Ensure accurate, reproducible results in immunofluorescence and flow cytometry applications with Thermo Scientific CD137 (4-1BB) Ab-1, Mouse Monoclonal Antibody.4-1BB (also known as CD137) is an inducible receptor-like protein expressed on the cell surface of activated splenic T cells and thymocytes. It exists as both a monomer and a dimer on the surface of activated T cells. 4-1BB is structurally related to the members of NGFR/TNFR superfamily which are characterized by the presence of three-six patterns of a cysteine-rich motif in their extracellular domains. Other members of this family include low affinity NGFR, two receptors for TNF (TNFR-I & TNFR-II), CD30, CD40, OX40, Fas, and CD27. These molecules are involved in cell growth, survival, and death processes. The cytoplasmic domain of 4-1BB include two runs of acidic amino acids, a potential p56lck binding site, five consecutive glycines at the C-terminus, and four potential phosphorylation sites: one tyrosine, two threonine, and one serine.
Host Species: Mouse
Species Reactivity: Human. Others not known.
Immunogen: Ectodomain of human 4-1BB recombinant protein
Molecular Weight: 30kDa
Positive Control: Spleen, thymus or tonsil
Cellular Localization: Membrane
- Flow Cytometry
USA: RUO; Int'l: RUO
|Ectodomain of human 4-1BB recombinant protein|
|Flow Cytometry, Immunofluorescence|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok