CD14, APC, clone: FWKW, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA112257
CD14 is a single-copy gene encoding 2 protein forms: a 50- to 55-kD glycosylphosphatidylinositol-anchored membrane protein (mCD14) and a monocyte or liver-derived soluble serum protein (sCD14) that lacks the anchor. Both molecules are critical for lipopolysaccharide (LPS)-dependent signal transduction, and sCD14 confers LPS sensitivity to cells lacking mCD14. Increased sCD14 levels are associated with inflammatory infectious diseases and high mortality in gram-negative shock.
|White blood cells.|
|PBS with 0.2% carrier protein and 0.08% sodium azide|
|monocyte differentiation antigen CD14, myeloid cell-specific leucine-rich glycoprotein|
|Store at 4°C, do not freeze|
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