CD14 Mouse anti-Human, Non-human primate, Biotin, Clone: MEM-18, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA119489
CD14 is a 55kDa GPI-anchored glycoprotein, constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils, where serves as a multifunctional lipopolysaccharide receptor; it is also released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 is able to discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. CD14 affects allergic, inflammatory and infectious processes.
|PBS with 15mM sodium azide; pH 7.4|
|monocyte differentiation antigen CD14, myeloid cell-specific leucine-rich glycoprotein|
|4° C, do not freeze|
|Human urinary proteins from the urine of a patient suffering from proteinuria.|
|Human, Non-human Primate|
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