CD13/CD14 Mouse anti-Human, FITC, PE, Invitrogen
Manufacturer: Invitrogen MA112204
This antibody is a monoclonal mixture of FITC-conjugated CD14 (clone FWKW, isotype IgG2b) and PE-conjugated CD13 (clone E735, isotype IgG1).CD14 is a single-copy gene encoding 2 protein forms: a 50- to 55-kD glycosylphosphatidylinositol-anchored membrane protein (mCD14) and a monocyte or liver-derived soluble serum protein (sCD14) that lacks the anchor. Both molecules are critical for lipopolysaccharide (LPS)-dependent signal transduction, and sCD14 confers LPS sensitivity to cells lacking mCD14. Increased sCD14 levels are associated with inflammatory infectious diseases and high mortality in gram-negative shock. This antibody recognizes the human CD13 cell surface glycoprotein, a 150kD molecule expressed by granulocytes and monocytes, and by myeloid leukemia cells. Inhibits infection of cells by human coronavirus, inhibits aminopeptidase N activity of the CD13 molecule immunoprecipitates. MA1-22542 detects CD13 in Human samples.
|human cell line KG-1a|
|PBS with 0.2% carrier protein and 0.08% sodium azide|
|ANPEP, AP-M, AP-N, Apn, Cd13, P150, alanyl aminopeptidase, aminopeptidase M, aminopeptidase N, aminopeptidase N/CD13, membrane protein p161, microsomal aminopeptidase, monocyte differentiation antigen CD14, myeloid cell-specific leucine-rich glycoprotein|
|4° C, do not freeze|
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