CD147 (soluble) Mouse anti-Human, Clone: MEM-M6/1, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA119201
CD147 (basigin, neurothelin, OX-47, 5A11, CE9, M6) also known as EMMPRIN (extracellular matrix metalloproteinase inducer) or TCSF (tumour cell-derived collagenase-stimulatory factor) is an ubiquitously expressed cell surface protein with multiple glycosylated forms. The highest level of CD147 expression is on metabolically active cells, such as lymphoblasts, inflammatory cells, brown adipocytes and malignant tumour cells. CD147 has multiple functions, including facilitating of cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulation of integrin functions, it plays roles in cell development and activation, fetal development or retinal function.This antibody recognizes an epitope in the N-terminal Ig domain (D1) of CD147 (Neurothelin), a 50-60kDa type I transmembrane glycoprotein primarily expressed on all leukocytes, red blood cells, platelets and endothelial cells; it is not expressed by resting lymphocytes. This is a high-affinity antibody capable of binding to unstimulated peripheral blood T cells.
|PBS with 15mM sodium azide; pH 7.4|
|5F7, CD147, EMMPRIN, M6, OK, TCSF, CD147 antigen, OK blood group antigen, basigin, collagenase stimulatory factor, extracellular matrix metalloproteinase inducer, leukocyte activation antigen M6, tumor cell-derived collagenase stimulatory factor|
|4° C, do not freeze|
|Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot|
|Protein A-CR purified soluble recombinant form of CD147.|
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