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CD147 (soluble) Mouse anti-Human, Clone: MEM-M6/1, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA119201

Catalog No. 01-675-965


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Description

Description

CD147 (basigin, neurothelin, OX-47, 5A11, CE9, M6) also known as EMMPRIN (extracellular matrix metalloproteinase inducer) or TCSF (tumour cell-derived collagenase-stimulatory factor) is an ubiquitously expressed cell surface protein with multiple glycosylated forms. The highest level of CD147 expression is on metabolically active cells, such as lymphoblasts, inflammatory cells, brown adipocytes and malignant tumour cells. CD147 has multiple functions, including facilitating of cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulation of integrin functions, it plays roles in cell development and activation, fetal development or retinal function.

This antibody recognizes an epitope in the N-terminal Ig domain (D1) of CD147 (Neurothelin), a 50-60kDa type I transmembrane glycoprotein primarily expressed on all leukocytes, red blood cells, platelets and endothelial cells; it is not expressed by resting lymphocytes. This is a high-affinity antibody capable of binding to unstimulated peripheral blood T cells.
Specifications

Specifications

CD147 (soluble)
Monoclonal
1mg/mL
PBS with 15mM sodium azide; pH 7.4
P35613
5F7, CD147, EMMPRIN, M6, OK, TCSF, CD147 antigen, OK blood group antigen, basigin, collagenase stimulatory factor, extracellular matrix metalloproteinase inducer, leukocyte activation antigen M6, tumor cell-derived collagenase stimulatory factor
Murine
IgG1
100μg
4° C, do not freeze, do not freeze
Primary
682
Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
MEM-M6/1
Unconjugated
BSG
Liquid
BSG
Protein A-CR purified soluble recombinant form of CD147.
Protein A
RUO
Antibody
Monoclonal
Human
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