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CD147 (soluble) Mouse anti-Human, Porcine, Clone: MEM-M6/2, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA119410

Catalog No. 01-676-158


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Description

Description

This antibody recognizes the extracellular Ig domain D1 of CD147 (Neurothelin), a 50-60 kDa type I transmembrane glycoprotein primarily expressed on all leukocytes, red blood cells, platelets and endothelial cells; it is not expressed by resting lymphocytes. This is a high-affinity antibody capable of binding to unstimulated peripheral blood T cells

CD147 (basigin, neurothelin, OX-47, 5A11, CE9, M6, EMMPRIN, extracellular matrix metalloproteinase inducer, TCSF, tumour cell-derived collagenase-stimulatory factor) is a 50-60 kDa glycoprotein with multiple glycosylated forms. CD147 is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is also a member of the immunoglobulin superfamily. The highest level of CD147 expression is on metabolically active cells, such as lymphoblasts, inflammatory cells, brown adipocytes and maligt tumor cells. CD147 has multiple functions, including facilitating of cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulation of integrin functions, it plays roles in cell development and activation, fetal development or retinal function.
Specifications

Specifications

CD147 (soluble)
Monoclonal
Unconjugated
BSG
Liquid
BSG
A soluble recombit form of CD147, CD147Rg, which consists of the cDNA coding for the entire extracellular region of CD147 fused to the DNA coding for the hinge region, CH2 and CH3 domain of human IgG1
Purified
RUO
Antibody
Monoclonal
Human, Porcine
Flow Cytometry, Immunohistochemistry (Paraffin)
MEM-M6/2
PBS with 15mM sodium azide; pH 7.4
P35613
5F7, CD147, EMMPRIN, M6, OK, TCSF, CD147 antigen, OK blood group antigen, basigin, collagenase stimulatory factor, extracellular matrix metalloproteinase inducer, leukocyte activation antigen M6, tumor cell-derived collagenase stimulatory factor
Mouse
IgG2b
100 μg
4° C, do not freeze
Primary
100141312, 682
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