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SSEA1 Mouse anti-Human, FITC, Clone: MEM-158, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA119562

Catalog No. 01-676-292


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Description

Description

CD15 (Lewis X, Le(x); stage specific embryonic antigen-1, SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. There are several variants of Lewis x, such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation, based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin´s disease.

This antibody will not cross-react with porcine, bovine or sheep.
Specifications

Specifications

SSEA1
Monoclonal
FITC
Liquid
FUT4
Human granulocytes.
Purified
RUO
Antibody
Monoclonal
Flow Cytometry
MEM-158
TBS with 15mM sodium azide
stage-specific embryonic antigen 1; CD15; SSEA-1; SSEA1; ELFT; FCT3A; FUC-TIV; FUTIV; LeX
Mouse
IgM
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
Human
Documents
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