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CD16 Mouse anti-Human, Brilliant Violet 421, Clone: 3G8, BD
Mouse Monoclonal Antibody
Supplier: BD Biosciences 562878
Description
The 3G8 monoclonal antibody specifically binds to the 50-65 kDa transmembrane form of the IgG Fc Receptor (FcγRIII), a human NK-cell-associated antigen. CD16 is expressed on NK cells as well as macrophages and granulocytes. Reports indicate that CD16 plays a role in signal transduction and NK cell activation. The 3G8 antibody blocks the binding of soluble immune complexes to granulocytes.
The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon™ Brilliant Violet™ family of dyes. With an Ex Max of 407nm and Em Max at 421nm, BD Horizon™ BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50nm filter). BD Horizon™ BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue™ conjugates.
Host Species: Mouse
Clone: 3G8
Isotype: IgG1, κ
Species Reactivity: Hu
Immunogen: Human polymorphonuclear leukocytes
Flow Cytometry
Specifications
CD16 | |
Monoclonal | |
Brilliant Violet 421 | |
Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
Human polymorphonuclear leukocytes | |
25 Tests | |
Primary | |
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
Flow Cytometry | |
3G8 | |
FcRIII; Fc-gamma RIII; FCG3; FCGR3; FCGRIII; FcγRIII; IGFR3 | |
Mouse | |
Affinity Purified | |
RUO | |
Baboon, Cynomolgus, Human, Rhesus Monkey | |
IgG1 κ |
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For Research Use Only.