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CD177 Mouse anti-Human, Non-human primate, Clone: MEM-166, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA119250

Catalog No. 01-676-014


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Description

Description

CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31 (PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).

Western blot should be performed under non-reducing conditions.
Specifications

Specifications

CD177
Monoclonal
1 mg/mL
PBS with 15mM sodium azide; pH 7.4
Q8N6Q3
HNA-2a, HNA2A, NB1, NB1 GP, PRV-1, PRV1, CD177 antigen, NB1 glycoprotein, cell surface receptor, human neutrophil alloantigen 2a, polycythemia rubra vera 1, polycythemia rubra vera protein 1
Mouse
IgG1
100 μg
4° C, do not freeze
Primary
57126
Flow Cytometry, Immunoprecipitation, Western Blot
MEM-166
Unconjugated
CD177
Liquid
CD177
Human granulocytes.
Protein A
RUO
Antibody
Monoclonal
Human, Non-human Primate
Documents
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