CD177 Mouse anti-Human, Non-human primate, Clone: MEM-166, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA119250
CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31 (PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).Western blot should be performed under non-reducing conditions.
|PBS with 15mM sodium azide; pH 7.4|
|HNA-2a, HNA2A, NB1, NB1 GP, PRV-1, PRV1, CD177 antigen, NB1 glycoprotein, cell surface receptor, human neutrophil alloantigen 2a, polycythemia rubra vera 1, polycythemia rubra vera protein 1|
|4° C, do not freeze|
|Flow Cytometry, Immunoprecipitation, Western Blot|
|Human, Non-human Primate|
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