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CCR8 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA112539

Catalog No. 01-674-199


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Description

Description

A suggested positive control for this product is human spleen lysate.

CCR8, a Chemokine Receptor, binds the CC-chemokine I-309, which is secreted by umbilical vein endothelial cells. CCR8 also binds viral monocyte inflammatory protein-I (vMIP-I), which is induced by Kaposi sarcoma-related human herpesvirus-8. CCR8 induces endothelial chemotaxis and may function as an HIV-1 co-receptor on primary human cells, contributing to HIV-1-induced thymic pathogenesis (Lee et al., 2000). CCR8 expression has been reported in spleen and thymus, natural-killer cells, monocytes, and T cells, and at lower levels in peripheral blood leukocytes.
Specifications

Specifications

CCR8
Polyclonal
PBS with 0.02% sodium azide
P51685
CDw198, CKR-L1, CKRL1, CMKBR8, CMKBRL2, CY6, GPR-CY6, MGC129966, MGC129973, TER1
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
1237
Western Blot
Unconjugated
CCR8
Liquid
CCR8
Synthetic peptide corresponding to residues 183-201 of human CCR8.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Documents
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