The F10/21A3 monoclonal antibody specifically binds to CD1c. The CD1 family of transmembrane glycoproteins are structurally related to the classical major histocompatibility complex (MHC) proteins. CD1c is a type I transmembrane glycoprotein that forms heterodimers with beta-2-microglobulin. CD1c presents lipids and glycolipids of self or microbial origin to T cells. CD1c is expressed by Langerhans cells, dendritic cells, monocytes, cortical thymocytes, T cells, and some B cells.
|GM-CSF- and IL-4-activated Human Monocytes|
|Alexa Fluor 647|
|CD1; R7; M241; BDCA1|
|Aqueous buffered solution containing BSA and ≤0.09% sodium azide|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
For Research Use Only.
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