CD1e Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA526941
DescriptionCD1E encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form. The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members.
|PBS with 0.09% sodium azide|
|CD1A, R2, CD1E antigen, e polypeptide, R2G1, T-cell surface glycoprotein CD1e, membrane-associated, differentiation antigen CD1-alpha-3, hCD1e, leukocyte differentiation antigen, thymocyte antigen CD1E, HCD1e|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|KLH conjugated synthetic peptide between 184-212 amino acids from the central region of human CD1E|
|Protein A, Antigen Affinity Chromatography|
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