CD200 Mouse anti-Human, FITC, Clone: MRC OX104, Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA135930
DescriptionCD200 is a type-1 membrane glycoprotein that contains two immunoglobulin domains, and belongs to the immunoglobulin superfamily. CD200 is a broadly distributed cell surface glycoprotein that interacts with a receptor on myeloid cells (CD200R) and is implicated in locally preventing macrophage activation. Distant, but recognizable, homologues of CD200 have been identified in many herpesviruses and poxviruses. Studies of the related genes in mouse and rat suggest that CD200 may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms of CD200 have been found. Diseases associated with CD200 dysfunction include Mantle Cell Lymphoma and Primary Hypertrophic Osteoarthropathy.
|PBS with 1% BSA and 0.09% sodium azide|
|My033, MOX1, MOX2, MRC, OX-2, CD200 antigen, MRC OX-2 antigen, OX-2 membrane glycoprotein, antigen identified by monoclonal antibody MRC OX-2|
|4° C, store in dark|
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