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CD200 Mouse anti-Human, APC, Clone: 325516, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA523575

Catalog No. PIMA523575


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Description

Description

In direct ELISAs, no cross-reactivity with recombit mouse CD200 is observed.

CD200 is a type-1 membrane glycoprotein that contains two immunoglobulin domains, and belongs to the immunoglobulin superfamily. CD200 is a broadly distributed cell surface glycoprotein that interacts with a receptor on myeloid cells (CD200R) and is implicated in locally preventing macrophage activation. Distant, but recognizable, homologues of CD200 have been identified in many herpesviruses and poxviruses. Studies of the related genes in mouse and rat suggest that CD200 may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms of CD200 have been found. Diseases associated with CD200 dysfunction include Mantle Cell Lymphoma and Primary Hypertrophic Osteoarthropathy.
Specifications

Specifications

CD200
Monoclonal
APC
CD200
Liquid
CD200
Mouse myeloma cell line NS0-derived recombit human CD200 Gln31-Gly232
Protein A/G
RUO
Antibody
Monoclonal
Human
Flow Cytometry
325516
Buffered saline solution with BSA and 0.09% sodium azide
P41217
My033, MOX1, MOX2, MRC, OX-2, CD200 antigen, MRC OX-2 antigen, OX-2 membrane glycoprotein, antigen identified by monoclonal antibody MRC OX-2
Mouse
IgG1
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
4345
Documents
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