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CD200 Mouse anti-Human, Clone: 325531, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA523912
In sandwich ELISAs, no cross-reactivity or interference with Recombinant mouse CD200 is observed. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.01 EU per 1 µg of the antibody by the LAL method.CD200 is a type-1 membrane glycoprotein that contains two immunoglobulin domains, and belongs to the immunoglobulin superfamily. CD200 is a broadly distributed cell surface glycoprotein that interacts with a receptor on myeloid cells (CD200R) and is implicated in locally preventing macrophage activation. Distant, but recognizable, homologues of CD200 have been identified in many herpesviruses and poxviruses. Studies of the related genes in mouse and rat suggest that CD200 may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms of CD200 have been found. Diseases associated with CD200 dysfunction include Mantle Cell Lymphoma and Primary Hypertrophic Osteoarthropathy.
|PBS with 5% trehalose and No Preservative|
|My033, MOX1, MOX2, MRC, OX-2, CD200 antigen, MRC OX-2 antigen, OX-2 membrane glycoprotein, antigen identified by monoclonal antibody MRC OX-2|
|-20° C, Avoid Freeze/Thaw Cycles|
|Mouse myeloma cell line NS0-derived recombit human CD200 Gln31-Gly232|
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