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CD200 Mouse anti-Human, Clone: 325531, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA523912

Catalog No. PIMA523912



Description

Description

In sandwich ELISAs, no cross-reactivity or interference with Recombinant mouse CD200 is observed. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.01 EU per 1 µg of the antibody by the LAL method.

CD200 is a type-1 membrane glycoprotein that contains two immunoglobulin domains, and belongs to the immunoglobulin superfamily. CD200 is a broadly distributed cell surface glycoprotein that interacts with a receptor on myeloid cells (CD200R) and is implicated in locally preventing macrophage activation. Distant, but recognizable, homologues of CD200 have been identified in many herpesviruses and poxviruses. Studies of the related genes in mouse and rat suggest that CD200 may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms of CD200 have been found. Diseases associated with CD200 dysfunction include Mantle Cell Lymphoma and Primary Hypertrophic Osteoarthropathy.
Specifications

Specifications

CD200
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
P41217
My033, MOX1, MOX2, MRC, OX-2, CD200 antigen, MRC OX-2 antigen, OX-2 membrane glycoprotein, antigen identified by monoclonal antibody MRC OX-2
Mouse
IgG1
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
4345
ELISA, Neutralization
325531
Unconjugated
CD200
Lyophilized
CD200
Mouse myeloma cell line NS0-derived recombit human CD200 Gln31-Gly232
Protein A/G
RUO
Antibody
Monoclonal
Human
Documents
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