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CD200R Mouse anti-Human, Clone: 380525, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524119

Catalog No. PIMA524119


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Description

Description

In direct ELISAs and Western blots, no cross-reactivity with recombit mouse CD200 R1 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

CD200R (OX2R) is a receptor for the OX-2 membrane glycoprotein, and both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. CD200R is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal. In mouse, CD200R is expressed primarily by peripheral blood monocytes and neutophils but also by other leucocytes including T-lymphocytes and mast cells. Further mouse studies of a gene related to CD200R suggests that the receptor may control myeloid function in a tissue-specific manner. Alternative splicing of CD200R results in multiple transcript variants. Diseases associated with CD200R dysfunction include primary hypertrophic osteoarthropathy.
Specifications

Specifications

CD200R
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
Q8TD46
CD200 R1, CD200R1, MOX2R, CD200 receptor 1, CD200RMOX2Rcell surface glycoprotein CD200 receptor 1, Cell surface glycoprotein OX2 receptor 1, cell surface glycoprotein receptor CD200, CRTR2, HCRTR2, MOX2 receptor, OX2RCD200 cell surface glycoprotein receptor
Mouse
IgG2B
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
131450
Flow Cytometry, Western Blot
380525
Unconjugated
CD200R1
Lyophilized
CD200R1
Mouse myeloma cell line NS0-derived recombit human CD200 R1 Ala27-Leu266 (predicted)
Protein A/G
RUO
Antibody
Monoclonal
Human
Documents
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