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CD205 Mouse anti-Human, FITC, Clone: MG38, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA135934

Catalog No. 01672425


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Description

Description

CD205 (LY25, Lymphocyte Antigen 75) is an integral membrane glycoprotein involved in antigen uptake, trafficking and presentation that improves the induction of antigen-specific T cell immunity. CD205 is highly expressed by CD8+ dendritic cells (DCs) and also expressed at different levels by bone marrow Gr1+ cells, Langerhans cells, (BMDC) bone marrow derived DCs and thymic epithelial cells. CD205 acts as an endocytic receptor that directs captured antigens to the extracellular space towards a specialized antigen processing region. Further, CD205 also prompts the reduced proliferation of B lymphocytes. Diseases associated with CD205 dysfunction include pneumonic plague and lipid pneumonia.
Specifications

Specifications

CD205
Monoclonal
FITC
LY75
Liquid
LY75
CR-Fn II fusion protein.
Purified
RUO
Antibody
Monoclonal
Human
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation
MG38
PBS with 1% BSA and 0.09% sodium azide
O60449
RP23-10L17.4, CD205, DEC-205, ly-75, CLEC13B, GP200-MR6, DCL-1 fusion, LY75-CD302 fusion protein
Mouse
IgG2b
100 μg
4° C, store in dark
Primary
4065
Documents
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