CD205 Mouse anti-Human, FITC, Clone: MG38, Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA135934
DescriptionCD205 (LY25, Lymphocyte Antigen 75) is an integral membrane glycoprotein involved in antigen uptake, trafficking and presentation that improves the induction of antigen-specific T cell immunity. CD205 is highly expressed by CD8+ dendritic cells (DCs) and also expressed at different levels by bone marrow Gr1+ cells, Langerhans cells, (BMDC) bone marrow derived DCs and thymic epithelial cells. CD205 acts as an endocytic receptor that directs captured antigens to the extracellular space towards a specialized antigen processing region. Further, CD205 also prompts the reduced proliferation of B lymphocytes. Diseases associated with CD205 dysfunction include pneumonic plague and lipid pneumonia.
|CR-Fn II fusion protein.|
|Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation|
|PBS with 1% BSA and 0.09% sodium azide|
|RP23-10L17.4, CD205, DEC-205, ly-75, CLEC13B, GP200-MR6, DCL-1 fusion, LY75-CD302 fusion protein|
|4° C, store in dark|
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