CD207 (Langerin) Mouse anti-Mouse, Alexa Fluor 647, Clone: 81E2, BD
Mouse Monoclonal Antibody
Manufacturer: BD Biosciences 564937
The 81E2 monoclonal antibody specifically binds to CD207 which is also known as Langerin, Langerhans cell specific c-type lectin, or C-type lectin domain family 4 member K (Clec4K). CD207 is a type II transmembrane glycoprotein that belongs to the C-type lectin family. CD207 is selectively expressed by Langerhans cells, an immature dendritic cell type that is found in the epidermis and mucosal epithelia, and by some other dendritic cell subsets. CD207 is expressed on the cell surface membrane and by intracellular Birbeck granules whose formation depends on CD207. CD207 binds to certain surface carbohydrates that are expressed by microbes. It appears to play a role in the uptake of these microbes for subsequent processing and microbial antigen presentation to T cells.
|Alexa Fluor 647|
|Aqueous buffered solution containing ≤0.09% sodium azide.|
|Cd207; Langerin; Clec4k; CLC4K|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
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