Langerin (CD207) Mouse anti-Human, Unlabeled, Clone: 2G3 (also known as AB5_8.2G3.6 ), BD
Mouse Monoclonal Antibody
Manufacturer: BD Biosciences 564789
The 2G3 monoclonal antibody specifically binds to Langerin which is also known as CD207 or C-type lectin domain family 4 member K (CLEC4K). CD207 is a 48 kDa type II transmembrane glycoprotein that belongs to the C-type lectin family. CD207 is selectively expressed by Langerhans cells, an immature dendritic cell type that is found in the epidermis and mucosal epithelia, and by some other dendritic cell subsets. CD207 is expressed on the cell surface membrane and by intracellular Birbeck granules whose formation depends on CD207. CD207 binds to certain surface carbohydrates that are expressed by microbes. It appears to play a role in the uptake of these microbes for subsequent processing and microbial antigen presentation to T cells.
|2G3 (also known as AB5_8.2G3.6 )|
|Aqueous buffered solution containing ≤0.09% sodium azide.|
|Store undiluted at 4°C|
|CLC4K; CLEC4K; C-type lectin domain family 4 member K|
|Human Langerin Recombinant Protein|
|The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.|
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