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CD21 Mouse anti-Human, PE-CF594, Clone: B-LY4, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 563474

Catalog No. BDB563474


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Description

Description

The B-ly4 monoclonal antibody specifically binds to CD21, a 145 kDa glycosylated type I integral membrane protein. CD21 is a receptor for the C3d complement fragment and for Epstein-Barr virus (EBV). CD21 is expressed on mature B cells, follicular dendritic cells, and some epithelial cells. It is also weakly expressed on the subset of mature T cells and thymocytes. CD21 plays a role in B-cell activation and proliferation. It may also play a role in modulating the function of T cells in the immune response to infections by lymphotropic viruses. Recently, CD21 was found to be part of a large complex containing CD19, CD81, and possibly other molecules.

This antibody is conjugated to BD Horizon™ PE-CF594, which has been developed exclusively by BD Biosciences as a better alternative to PE-Texas Red™. PE-CF594 excites and emits at similar wavelengths to PE-Texas Red™ yet exhibits improved brightness and spectral characteristics. Due to PE having maximal absorption peaks at 496nm and 564nm, PE-CF594 can be excited by the blue (488-nm), green (532-nm) and yellow-green (561-nm) lasers and can be detected with the same filter set as PE-Texas Red™ (eg 610/20-nm filter).

Specifications

Specifications

CD21
B-LY4
CR2; Complement receptor type 2; C3DR; EBV-R; Epstein-Barr virus receptor
Affinity Purified
IgG1, κ
RUO
Primary
Baboon, Canine, Cynomolgus, Human, Porcine, Rhesus
Flow Cytometry
PE-CF594
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Murine
100 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Documents
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