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CD221 Mouse anti-Human, Unlabeled, Clone: 3B7, BD
Mouse Monoclonal Antibody
Supplier: BD Biosciences 556000
Description
Reacts with human insulin-like growth factor-I (IGF-I) receptor. IGF-I receptor is a glycoprotein complex composed of two extracellular α subunits and two transmembrane β subunits. The transmembrane subunits play a role in tyrosine phosphorylation of several intracellular signaling proteins. IGF-I receptor is structurally and functionally similar to insulin receptor and is expressed on a variety of human hematopoietic and non-hematopoietic cells. 3B7 antibody does not cross react with human insulin receptor; it stimulates IGF-I and IGF-II induced cell growth and activates autophosphorylation of the IGF-I receptor β subunit.
Specifications
| CD221 | |
| Monoclonal | |
| 0.5mg/mL | |
| IGF-I receptor | |
| Mouse | |
| 0.1 mg | |
| Immunology | |
| Human | |
| IgG1 κ |
| Flow Cytometry | |
| 3B7 | |
| Unconjugated | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C |
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