Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

CD23 Mouse anti-Human, Alexa Fluor 700, Clone: M-L233, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 563673

Catalog No. BDB563673


Add to cart

Description

Description

The M-L233 antibody specifically binds to human CD23, the low affinity receptor for human IgE (Fc ε RII). CD23 is a type II membrane glycoprotein that can be expressed by B cells, monocytes, macrophages, eosinophils, platelets and dendritic cells. CD23 can mediate IgE-dependent cytotoxicity and phagocytosis by macrophages and eosinophils. Soluble CD23 (sCD23) can be released by CD23-positive cells as a result of proteolytic cleavage of membrane CD23. Larger fragments of sCD23 (e.g., 25-37 kDa) retain their IgE-binding capacity whereas smaller fragments (i.e., ≤ 12 kDa) do not. Soluble CD23 may have immunoregulatory effects on the growth and differentiation of B cells and other cell types.

Specifications

Specifications

CD23
M-L233
FCER2; FcεRII; Low affinity immunoglobulin epsilon Fc receptor; BLAST-2
Affinity Purified
IgG1, κ
RUO
Primary
Human
Flow Cytometry
Alexa Fluor 700
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Murine
100 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit