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CD23 Rat anti-Mouse, PE, Clone: 691632, Invitrogen™

Rat Monoclonal Antibody

Manufacturer:  Invitrogen MA523612

Catalog No. PIMA523612


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Description

Description

In direct ELISAs, no cross-reactivity with Recombinant human (rh) Fc epsilon RIA or rhFc epsilon RIG is observed.

CD23 is a 45 kDa glycoprotein which is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is identical to the low affinity IgE receptor found on B cells. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocyctic leukaemia and some cases of centroblastic/centrocytic lymphoma. CD23 is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. Functionally, CD23 is involved in B cell growth and differentiation, and IgE production. Further, CD23 has a soluble form that is a potent mitogenic factor. Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.
Specifications

Specifications

CD23
Monoclonal
PE
Fcer2a
Liquid
Fcer2a
Mouse myeloma cell line NS0-derived recombit mouse CD23/Fcepsilon RII Glu50-Pro331
Protein A/G
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry
691632
Buffered saline solution with BSA and 0.09% sodium azide
P20693
CD23, CD23A, CLEC4J, FCE2, IGEBF, BLAST-2, C-type lectin domain family 4, member J, CD23 antigen, fc-epsilon-RII, immunoglobulin E-binding factor, low affinity immunoglobulin epsilon Fc receptor, lymphocyte IgE receptor
Rat
IgG2A
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
14128
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