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CD23 Mouse anti-Human, PE, Clone: LVNC-4, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA112065

Catalog No. 01-670-788


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Description

Description

CD23 is a 45 kDa glycoprotein which is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is identical to the low affinity IgE receptor found on B cells. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocyctic leukaemia and some cases of centroblastic/centrocytic lymphoma. CD23 is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. Functionally, CD23 is involved in B cell growth and differentiation, and IgE production. Further, CD23 has a soluble form that is a potent mitogenic factor. Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.
Specifications

Specifications

CD23
Monoclonal
PE
FCER2
Liquid
FCER2
White blood cells.
Protein A/G
RUO
Antibody
Monoclonal
Human
Flow Cytometry
LVNC-4
PBS with 0.2% carrier protein and 0.08% sodium azide
P06734
CD23, CD23A, CLEC4J, FCE2, IGEBF, BLAST-2, C-type lectin domain family 4, member J, CD23 antigen, fc-epsilon-RII, immunoglobulin E-binding factor, low affinity immunoglobulin epsilon Fc receptor, lymphocyte IgE receptor
Mouse
IgG1
100 Tests
4° C, do not freeze
Primary
2208
Documents
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