CD275 (B7-H2) Mouse anti-Human, Clone: GM13C1, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA117756
This antibody recognizes native human ICOSL protein expressed in transfected mammalian cells.Inducible co-stimulator ligand (ICOSL) is a specific ligand on antigen-presenting cells and cells of the peripheral tissue that binds to the inducible co-stimulator receptor (ICOS). ICOS belongs to the CD28/CD152 receptor family that regulates T-cell activation and function. ICOSL is expressed on monocytes, dendritic cells and B cells and can be induced by inflammatory stimuli in peripheral tissue. Binding to ICOSL delivers a co-stimulatory signal for T cell proliferation and cytokine secretion.
|PBS with 0.01% sodium azide; pH 7.2|
|B7-H2, B7H2, B7RP-1, B7RP1, CD275, GL50, ICOS-L, ICOSL, KIAA0653, LICOS, ICOS Ligand|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|ELISA, Flow Cytometry|
|cDNA encoding human ICOSL|
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