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TLR4 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA112824

Catalog No. 01-675-815


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Description

Description

A suggested positive control for this product is placenta, spleen or peripheral blood leukocytes.

Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) á/â and NF- êB (4-6). Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide. Consequently, these mice also showed increased susceptibility to Gram-negative sepsis.
Specifications

Specifications

TLR4
Polyclonal
Unconjugated
TLR4
Liquid
TLR4
Synthetic peptide corresponding to 15 residues near the N-terminus of human TLR4.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunocytochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
O00206
Toll-like Receptor 4, ARMD10, CD284, TLR-4, TOLL, hToll, homolog of Drosophila toll
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
7099
Documents
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