Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

CD29 Mouse, Unlabeled, Clone: 18, BD

Mouse Monoclonal Antibody

$225.00 - $445.00

Specifications

Antigen CD29
Isotype IgG1
Immunogen Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Formulation Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Conjugate Unconjugated
View More Specs

Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
BDB610467
View Documents
BD Biosciences
610467
50μg Each for $225.00
Add to cart
 
BDB610468
View Documents
BD Biosciences
610468
150μg Each for $445.00
Add to cart
 
Description

Description

Integrins are membrane receptors that mediate cell-cell or cell-matrix adhesion. All integrins are transmembrane heterodimers composed of α and β subunits and are connected to the cytoskeleton. At least 20 integrins, formed from combinations of 12 α and 9 β subunits, have been reported. Many of these have been implicated as transducers of molecular signals. The β1 subgroup of this receptor family comprises at least six different dimer combinations. Among these combinations, α2β1 is associated with type I collagen and laminin binding and regulation, α3β1 is a receptor for laminin and epiligrin, and α5β1 is a fibronectin receptor. β1 integrins play an important role in several aspects of epidermal differentiation and morphogenesis. Expression of the β1 subunit is regulated by growth factors such as TGF-β1. Integrin activation, which enhances binding of T cells to endothelium, is regulated in part by phosphatidylinositol 3-kinase. Focal adhesion kinase (FAK) and paxillin have been reported to independently bind the C-terminal, cytoplasmic domain of the β1 subunit. FAK is reported to be enzymatically activated upon engagement of integrins with their ligands and paxillin is phosphorylated on tyrosine upon activation of FAK.

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

Specifications

Specifications

CD29
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Unconjugated
Immunology
Murine
Affinity Purified
Monoclonal
Integrin β1; platelet GPIIa; VLA β-chain
IgG1
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary
Western Blot
RUO
18
250μg/mL
Store undiluted at -20°C.

For Research Use Only.

Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit