CD3d Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA528313
PA5-28313 targets CD3 delta in WB applications and shows reactivity with Human samples. The PA5-28313 immunogen is recombit fragment corresponding to a region within amino acids 1 and 171 of Human CD3 delta. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.CD3d is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The CD3d protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in the CD3d gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms of CD3d have been found. Other variants of CD3d may also exist, but the full-length nature of their transcripts have yet to be defined.
|Recombit fragment corresponding to a region within amino acids 1 and 171 of Human CD3 delta|
|Antigen affinity chromatography|
|PBS with 20% glycerol and 0.01% thimerosal; pH 7|
|CD3-DELTA, T3D, CD3 antigen, delta subunit, CD3 delta, CD3d antigen, delta polypeptide TiT3 complex, OKT3, delta chain, T-cell receptor T3 delta chain, T-cell surface glycoprotein CD3 delta chain|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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