Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

CD3 + CD16 + CD56 FITC, PE Monoclonal Antibody, Clone: M2AB, C5.9, J5511, Invitrogen™

CD3 + CD16 + CD56 Antibody, FITC, PE conjugate (M2AB, C5.9, J5511), MA1-12207, from Invitrogen™. Species Reactivity: Human; Applications: Flow Cytometry.

Manufacturer:  Invitrogen MA112207

Catalog No. 01-670-917

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

CD3 + CD16 + CD56 Antibody, FITC, PE conjugate (M2AB, C5.9, J5511), MA1-12207, from Invitrogen. Species Reactivity: Human; Applications: Flow Cytometry.

T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation. CD16 is a 50-65kD cell surface molecule which exists in two forms - a transmembranous form expressed by NK cells and some T cells and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC by NK cells.
Host Species: Mouse
Cross Reactivity: Human
Isotype: IgG1/IgG2b
Clone: M2AB, C5.9, J5511
Immunogen: human thymocytes and NK lymphocytes
Formulation: 50 Tests purified antibody in PBS with 0.2% carrier protein and 0.08% sodium azide
Synonyms: CD3e, CD3 epsilon, FLJ18683, T3E, TCRE, CD3-epsilon, CD3e antigen, epsilon polypeptide TiT3 complex, T-cell antigen receptor complex, epsilon subunit of T3, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, FCGR3, FCGR3A, FCGR3B, CD16A, CD16B, Fc gamma Receptor III, Fc gamma Receptor 3, RP11-5K23.1, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, NCAM1, NCAM, CD-56, MSK39, neural cell adhesion molecule 1
Uniprot Accession: O75015, P04234, P07766, P08637, P09693, P13591
Entrez GeneID: 2214, 2215, 4684, 915, 916, 917
Gene Symbol: CD3D, CD3E, CD3G, FCGR3A, FCGR3B, NCAM1
This antibody is a monoclonal mixture of FITC-conjugated CD3 (clone M2AB, isotype IgG1), PE-conjugated CD56 (clone C5.9, isotype IgG2b) and PE-conjugated CD16 (clone J5511, isotype IgG1).
Specifications

Specifications

CD3/CD16/CD56
Monoclonal
FITC, PE
O75015, P04234, P07766, P08637, P09693, P13591
CD3e, CD3 epsilon, FLJ18683, T3E, TCRE, CD3-epsilon, CD3e antigen, epsilon polypeptide TiT3 complex, T-cell antigen receptor complex, epsilon subunit of T3, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, FCGR3, FCGR3A, FCGR3B, CD16A, CD16B, Fc gamma Receptor III, Fc gamma Receptor 3, RP11-5K23.1, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, NCAM1, NCAM, CD-56, MSK39, neural cell adhesion molecule 1
Murine
IgG1/IgG2b
RUO
Primary
Monoclonal
Human
Flow Cytometry
C5.9
50 Tests purified antibody in PBS with 0.2% carrier protein and 0.08% sodium azide
Purified
CD3D, CD3E, CD3G, FCGR3A, FCGR3B, NCAM1
human thymocytes and NK lymphocytes
50 Tests
Store at 4°C
Primary
2214, 2215, 4684, 915, 916, 917
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit