CD300e Rat anti-Human, Clone: 233810, Invitrogen
Rat Monoclonal Antibody
Manufacturer: Invitrogen MA523940
In direct ELISAs, no cross-reactivity with recombit human LMIR1, 2, 3, 4, or 5 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.CD300e is a member of the glycoprotein family of cell surface proteins expressed on myeloid cells. CD300e interacts with the TYRO protein tyrosine kinase-binding protein and is thought to be involved as an activating receptor. CD300e is expressed on mature myeloid dendritic cells and monocytes, and is down regulated on immature dendritic cells. Further, CD300e interacts with DAP-12, which mediates activating signals. The alloreactive response of naïve T cells has been reported to become enhanced by the activation of CD300e. Diseases associated with CD300e dysfunction include tungiasis and lice infestation.
|PBS with 5% trehalose and No Preservative|
|CMRF35-like molecule 2, CLM2, CD300 antigen-like family member E, CMRF35-A5, Immune receptor expressed on myeloid cells 2, IREM-2, Polymeric immunoglobulin receptor 2, PIgR-2, PIgR2, Poly-Ig receptor 2, CD300LE, CMRF35A5, IREM2, CLM-2|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Western Blot|
|Y3 rat myeloid cell line transfected with human CD300e/LMIR6|
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