CD321 (JAM-1) Rat anti-Mouse, PE, Clone: H202-106, BD
Rat Monoclonal Antibody
Manufacturer: BD Biosciences 564908
The H202-106 monoclonal antibody specifically binds to CD321 which is also known as JAM-1 (Junctional adhesion molecule 1), Junctional adhesion molecule A (JAM-A), and F11 Receptor (F11R). CD321 is a type I transmembrane glycoprotein that includes two extracellular immunoglobulin-like domains. CD321 functions as an adhesion receptor molecule on platelets. It also supports the tight junction formation between endothelial cells, where it may regulate the transendothelial migration of leucocytes, and some epithelial cells. CD321 expression by certain subsets of tissue-derived, MHC Class II-positive thymic epithelial cells, macrophages, and dendritic cells suggest that it may play a role in the organization and function of antigen presenting cells.
|Aqueous buffered solution containing ≤0.09% sodium azide.|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
|F11r; F11 receptor; JAM; JAM-A; Jam1; Jcam; Jcam1; Ly106|
|Mouse Thymic Stromal Cell Line|
|The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.|
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