CD357 (AITR/GITR) Mouse anti-Human, Clone: 110416, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA523854
This antibody does not cross-react with recombit human (rh) 4-1BB, recombit mouse (rm) 4-1BB, rhCD27, rmCD27, rhCD30, rmCD30, rhCD40, rmCD40, rhDR3, rhDR6, rhEDAR, rmEDAR, rhFas, rmFAS, rmGITR, rhHVEM, rhLymphotoxin R beta, rmLymphotoxin R beta, rhNGF R, rhOPG, rmOPG, rhRANK, rmRANK, rhTAJ, rhTNF RI, rmTNF RI, rhTNF RII, or rmTNF RII. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.Glucocorticoid-induced tumor necrosis factor receptor family-related gene (GITR) is a member of the tumor necrosis factor receptor (TNFR) family that is expressed at low levels on unstimulated T cells, B cells, and macrophages. Upon activation, CD4+ and CD8+ T cells up-regulate GITR expression, whereas immunoregulatory T cells constitutively express high levels of GITR.
|PBS with 5% trehalose and No Preservative|
|Tumor necrosis factor receptor superfamily member 18, Activation-inducible TNFR family receptor, Glucocorticoid-induced TNFR-related protein, CD357, TNFRSF18, AITR, GITR, UNQ319, PRO364|
|-20° C, Avoid Freeze/Thaw Cycles|
|ELISA, Flow Cytometry, Neutralization, Western Blot|
|Mouse myeloma cell line NS0-derived recombit human GITR/TNFRSF18 Gln26-Glu161 (Thr43Ala)|
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